A design method of software based on Spacecraft PSS SCOE (Power Supply Special Check-out Equipment) is introduced. By using configuration files, this method is an effective solution for large complex system signals. The software covers the command control, parameter measurement and state detection function. The result shows that this software frame is convenient for PSS SCOE to manage Spacecraft with high level of integration and reliability. The software structure of PSS SCOE is elaborated, and can be used as a general software frame design.